The maximum speed limit will go up to 130 kph on Friday, transport authority Rijkswaterstaat says.
Parts of the A4, A5 and A32 will see an increase in the speed limit, but motorists will still face a plethora of differentiated limits.
While motorways allow drivers to travel at 130 kph on some stretches, in built-up areas speeds are reduced to as little as 80 kph to meet sound and pollution levels.
The government wants 60% of all motorways to have the new higher speed limit, but will not allow more roads to bring it in until safety regulations are met.
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