PSV are nine points clear of defending champions Ajax, who had a 2-0 win over Venlo on Saturday evening.
PSV’s closest challenger Twente could only manage a 1-1 draw at Utrecht, while third-placed Vitesse of Arnhem beat NEC 4-1. Transfer target Wilfried Bony scored two of Vitesse’s goals.
Feyenoord, currently in joint fourth place with Ajax, beat Willem II 3-0.
Match reports, fixtures and latest standings